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OBJECTIVE: To determine the effect of energy expenditure on pregnancy outcome. Methodology: A prospective cohort study was carried out at Ragama and Ja-ela MOH areas. Eight hundred and seventy five pregnant mothers were recruited at 16 weeks of gestation (POA). Daily energy expenditure was assessed based on the activities indicated by the pregnant mothers in the Activity Record1 on two occasions during 20 (371 subjects) and 32weeks of POA (271 subjects) at home by housewives and both at home and at work by working mothers. On each occasion activities related to 3 different days were recorded. Average energy expenditure was calculated and >2550 kcal/day was considered as the cut off. Information on potential confounding factors was gathered on average at 12th, 28s11 and 36 POA. Pregnancy outcome was assessed in terms of maternal complications (MC) such as pre-eclampsia, ante-partum haemorrhage and gestational diabetes, pre-term birth , low birth weight (LEW), small for gestational age <10dl (SGA<1O) and <5th (SGA<5) centiles. Logistic regression analysis was applied and the results are expressed as odds ratios (OR) and 95%
confidence intervals (95%CI). Results: Univarite analysis revealed that >2550 kcal/day energy expenditure during 20 weeks of POA was significantly associated with subsequent development of MC (OR6.86, 95% CP=2.38-19.76) and with MC (OR=1 1.03, 95%CFI.36-89.24), LBW (OR=O.05, 95% CI-O.006-0.36) and SGA<5 (OR=O.29, 95% CIO.10-0.87) during 32" xveek of POA. On multivariate analysis subsequent development of MC (OR=6.305 95% CI 21.94} and SGA<5 (OR=0.29, 95% CI = 0.09-O.96), remained significantly associated with high energy expenditure during 20 ' week of POA and 32"d week of POA respectively. CONCLUSION: High energy expenditure was a risk factor for maternal complications and a protective factor against the birth of a small for gestational age infant. |
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