Citation:Wijebandara, D.M.K.K., Peiris, K.P.P., Karunarathna, E.D.C. and Sudesh, A.D.H. (2017). A comparative study on the anti-microbial efficacy of two Ayurveda powders (Prathisarana) used in periodontal diseases. Salakya Sandipani, Department of Shalya Shalakya,Gampaha Wickramarachchi Ayurveda Institute,University of Kelaniya,Sri Lanka.p 129.
Date:2017
Abstract:
Kushtadi (KU) and Karanjadi (KR) are prominently used Ayurvedic powders (Prathisarana) in
the management of periodontal diseases. This study was carried out for the determination of
antimicrobial efcacy of these two drugs using standard Antimicrobial Sensitivity Test against
Candida albicans and a fungal culture isolated from a patient. The Antimicrobial Sensitivity Test
was performed according to the Well diffusion method having 6mm diameter wells on
Sabouraud Dextrose Agar (SDA). Each well was loaded with test drugs mixed in 20μl of sterile
distilled water and uconazole 2.5mg / ml as the positive control. According to the results, KR
showed an average Inhibition Zone Diameter (IZD) of 20mm for the isolated culture while KU
did not show any inhibition. The results were similar for Candida albicans, KR showing IZD 18
mm, KU IZD 0 mm while positive control showed an inhibition of 25 mm. Therefore, it can be
concluded that both Candida albicans and the isolated culture were sensitive only for KR
making it the only effective drug out of the two drugs tested in this study.
