Citation:Hemali, K.R., Varnakulendran, N. and Sivaganesan, S. (2017). Effectiveness of Lannea coromandelica (Houtt.) Merrill – Odhi root bark powder for wound healing activity in Wistar albino rats. Salakya Sandipani, Department of Shalya Shalakya,Gampaha Wickramarachchi Ayurveda Institute,University of Kelaniya,Sri Lanka.p 72.
Date:2017
Abstract:
Lannea coromandelica is a well-known tree that belongs to Anacardiacae family and is
commonly known as Odhi in Tamil and Hik in Sinhala. Although it has been used by traditional
physicians, still it has not been used in the preparation of pharmaceuticals. Root bark powder of
Lannea coromandelica was administered in 250g of wistar albino rats. Fine powder of root bark
of Lannea coromandelica was prepared. The animals were divided into 3 groups of 3 each. The
animals of group 1 were left untreated and considered as control. Group 2 served as the standard
and received Cloxacilline powder. Group 3 was considered as the test group and treated with the
prepared test drug.The Powder of test drug and the standard drug were topically applied twice a
day starting from the day of operation, untill complete epithelialization. Wounds were measured
in width and length in the scale of mm and the size of the wound was calculated. The appearance
of wound was reported as per Likert scale. The result of the study suggests the tested powder of
root bark of Lannea coromandelica has a signicant power of wound healing activity. The
wounds of all animals treated with test drug completely healed while the wounds of standard and
control groups persisted. It can be concluded that the root bark powder of Lannea coromandelica
has remarkable wound healing action in wistar albino rats.
