Citation:Peiris K.P.P., Samaranayake G.V.P., Wijebandara D.M.K.K.,A Comparative Study on the Anti-microbial efficacy of Two Ayurveda Powders (Prathisarana) Used in Periodontal Disease, International Journal of Dental Science and Innovative Research (IJDSIR), Volume 2, Issue 2, April 2019, ISSN 2581-5989, 407-411pp
Date:2019
Abstract:
Kushtadi (KU) and Karanjadi (KR) are prominently used
Ayurvedic powders (Prathisarana) in the management of
periodontal diseases. This study was carried out for the
determination of antimicrobial efficacy of these two drugs
using standard Antimicrobial Sensitivity Test against
Candida albicans and a fungal culture isolated from a
patient. The Antimicrobial Sensitivity Test was performed
according to the Well diffusion method having 6 mm
diameter wells on Sabouraud Dextrose Agar (SDA). Each
well was loaded with test drugs mixed in 20 gl of sterile
distilled water and fluconazole 2.5 mg/ml as the positive
control. According to the results, KR showed an average
Inhibition Zone Diameter (iZD) of 20 mm for the isolated
culture while KU did not show any inhibition. The results
were similar for Candida albicans and KR showing IZD
18 mm, KU IZD 0 mm while positive control giving an
Inhibition of 25 mm. Therefore, it can be concluded that
Candida albicans and the isolated culture were
sensitive Only for KR making it the only effective drug out
of the two drugs tested in this study.
