Determination of antimicrobial efficacv of four Ayurveda Local Applications (Pratisarana Yoga) in the management of Periodontal Disease

Abstract

This study evaluates the antimicrobial activity of four Ayurvedic formulations namely Kushtadi Ehurna, Swethamaniana Churna, Karanladi Churna and Dasana Sanskara Churna that are used to treat periodontal diseases as local applications. The objectives are to find out the presence or absence of in-vitro antimicrobial efficacy of these four drugs and to evaluate the antimicrobial efficacy of them using agar well diffusion method. The organisms used for the study are Staphylococcus aureus (ATCC 29213), Metlucillin resistant Staphylococcus aureus (ATCC 25923) and clinically isolated Candida albicans. The results of the in-vitro antimicrobial efficacy study reveals that Swethamanjana Chuma possesses antimicrobial action against all three tested microorganisms. Kushtadi Churna is cffcctivc against S. aureus (ATCC 29213) and MRSA (ATCC 25923) and it is unable ro affect rhe growth of C. albicans. Karaniadi Churna and Dasana Sanskara Chuma are effecnve against S. aureus (ATCC 29213) and C. albicans and not effective against MRSA(ATCC 25923). Fluconazole and Amoxicillin are used as positive controls for the yeast and two bacteria respectively.