Critical Study on the Pharmacological Activity of Emetic Drugs Used in Vamana Karma with Special Reference to Vruddhathraya

Abstract

Äyurveda is the science of life.lt deals with the total creation with special emphasis on the biology of life. The main objective being to relieve human suffering approach to the treatment of a disease consists of two major procedures. They are Vamana is the major pradhäna karma procedure of pancakarma therapy. It expels out the vitiated kapha dosha. Vamana is the ürdhavabhäga SamSodhana procedure. Literally vamana means to expel out of the vitiated doshas through the oral route.The expelled material may consist of indigested food, Kapha and Pitta. Varnana is the principal property of prthvi and jala mahä bhütas. There is an extensive discussion on vamano and vämaka drugs in Åyurvedic classics. Unavailability of scientific access information regarding pharmacological study of vamana karma.Most of the studied details regarding this are not available as one document or a text book. The knowledge of Pharmacology of Vamana dravya (pharmacodynamics and pharmacokinetics), Physiology of Vamana karma, pharmacognostical study and Phytochemistry of Varnana dravya mentioned in Ayuneda classics should be collected in order to review and critically analyze in this study. Emetic alkaloids of several plants can administrate for this Vamana karma.The phytochemical analysis of plants like Randia dumetorum, Cephelis, Ipecacuanha, Lagenaria Sicereria reveal that contains emetic alkaloids, emetine, Cephaeline and Protometine are some of phytochemicals that have the emetogenic property-In this study reveals the relationship between the pharmacological activities of relavant emetic chemicals and the pharmacological activity of chemical constituents of selected emetic materials which reference to Vruddhatraya.