Abstract:
Clnnamomum zeyJanlcum fs an evergreen tropical tree which Is proven to have hypoglycaemic
properties. Proa.nthocyanidins. which are phenolic compounds beJonging to the class of
flavonokls present in cinnamon are considered as the main bloactive component which imparts
a hypoglycaemic effect Alttlough oral hypoglycemic synthetic drugs can achieve this, synthetic
drugs cause severaJ skle effeClS on human health. Hence, the pu.rpose of this study was to
Investigate natural herbs that have fewer side effects for managing diabetes. Phytochemicats
lhat are respons!ble for the anti-diabetic properties rn two accessions of CJnnamomum
zeytallicum leaf, known as Sri Gemunu and Srt Wijaya, were 1es100 for lh8 hypoglY!J8mlc effect
Out of the three extraction methods; ethanollc extraction, hot water extraction and pressurized
hot water extraction, ethanolc extraclbn showed the highest extraction yield. The yield of Sri
Gemunu ethanolic extract was 6.20 % wtw and yield of Sri Wijaya ethanolic extract was 9.9%
w/w. Ethanollc extracts of the t'NO acoessions were tested for total phenolic content (20.60 t
0.01 mg gallic acid eq.g·' of Sri Gemunu. 6.07 ± 0.01 mg galllc acid e<j.g·' of Sri Wljaya), total
ftavanold content (72.02 ± 0.02 mg quercetin e<j.g·' of Sri Gemunu, 23.59 ± 0.02 mg quercetil
eq.g·• of Sri Wijaya) ,total proanthocyanldln con1ent (0.60 ± 0.05 g catechln eq.g-1 of Sri Gemunu,
0.15 ± 0.05 g catechln eq.g-1 of Sri Wi)aya) and DPPH radical scavenging activity (IC..58.18 ±
2.53 ~glml of Sri W13ya, 69.60 ± 5.48 ~glml of Sri Gemunu). GC.MS analysis and HPLC
analysis l'ldicated that both accessions were rich In eugenol and clnna.maldehyde. According to
the results of the study, ethanollc extract of leaves of Sri Gemunu Clnnamomum zeyfanlcum
accession displayed significant amounts of phytochemlcals that are related to the antl..ctlabetlc
properties compared to the leaves of Sri Wijaya.
