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Adverse events following first dose of ChAdOxI nCoV-19 (Covishield) among health care workers in Sri Lanka

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dc.contributor.author Manilgama, S.R.
dc.contributor.author Hettiarachchi, N.M.
dc.contributor.author Jayasinghe, I.K.
dc.contributor.author de Silva, S.
dc.contributor.author Jayalath, T.
dc.contributor.author Wanigaratne, T.
dc.contributor.author Bandusiri, R.P.
dc.contributor.author Suganthan, N.
dc.contributor.author Sudarshan, P.
dc.contributor.author Pathirage, M.
dc.contributor.author Rajaratnam, N.
dc.contributor.author Senaratne, G.
dc.contributor.author Rajapaksha, V.
dc.contributor.author Wickramasinghe, A.
dc.contributor.author Kulaweera, M.T.D.
dc.date.accessioned 2022-01-25T06:07:47Z
dc.date.available 2022-01-25T06:07:47Z
dc.date.issued 2021
dc.identifier.citation Asian Journal of Internal Medicine.2021:1(1);14. en_US
dc.identifier.isbn 978-624-5676-01-9 en
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/24406
dc.description Oral Presentation Abstract (OP08), 5th Annual Congress of the Sri Lanka College of Internal Medicine. 2021, 18th to 20th November Sri Lanka. en
dc.description.abstract Introduction: A community vaccination programme is crucial to combat COVID-19 pandemic. An independent post-vaccine surveillance is important to identify adverse events following immunization (AEFI) in the population. Objective: To estimate the prevalence of AEFI after covishield vaccination among all categories of health care workers (HCWs) after the first dose. Methods: A multicentred cross-sectional survey was conducted in six provinces. A self-administered questionnaire was used to gather demographic data and AEFI. Results: Of 5140, 67.8% were females. The mean (SD) age was 40.69 (±10.07) years. At least one comorbidity was reported in 15.4%, At least one AEFI was reported in 86.6% and 49.3% had local AEFI. Bodyaches(54.4%), headaches (57.3%), fever (58.4%), chills(51.2%)( fatigue(37.5%) and arthralgia (36%) were the most reported systemic AEFI. Majority lasted <24 hours. Pain and redness at the site were the most reported local AEFI. Mean duration of onset of fever and site of pain was 6.65 and 9.67 hours respectively. The population was divided into two groups according to the mean age; <40 and >40 years and, study parameters were compared. Most of the systemic (fever, nausea, fatigue, itching) and all local AEFI were significantly higher among the <40-year-old group. Reactions occurred within first 20 minutes in 2%. Anaphylaxes developed in 12 patients. History of an叩hylaxis, drug, or food allergies were reported in 0.6%, 2.8%, 6.7% respectively, they didn't show significant relation to current vaccine induced allergies or anaphylaxis. Despite having minor AEFI, 71.1% attended routine work while 0.2% were hospitalised and treated. en_US
dc.language.iso en en_US
dc.publisher Sri Lanka College of Internal Medicine en_US
dc.subject vaccination en_US
dc.subject COVID-19 en_US
dc.title Adverse events following first dose of ChAdOxI nCoV-19 (Covishield) among health care workers in Sri Lanka en_US
dc.type Article en_US


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