| dc.description.abstract |
Mind and body are intimately associated with each other. The function of body organs depends on
mental makeup of an individual and vice versa. Many factors such as stress, anxiety, depression, negative
thoughts, unhealthy life style, unwholesome diet etc., influence mental and physical wellbeing. In senile
Dementia progressive deterioration of memory, intellect, attention, thinking, comprehension and
personality etc, is encountered during old age with preservation of normal level of consciousness.
Medhyarasayana ghrita is a research based newly formulated medicine which contains sankhapushpi,
mandukaparni, yastimadhu, guduchi, jyotishmati, kushmanda, ashwagandha, tulsi,
bhallatak,kapikachchu and zinc processed with ghee. Vachadi ghrita in form of pratimarsha nasya
was administered along with oral Medhyarasayana ghrita. Vachadi ghrita nasya contains vacha,
kustha, pippali which also have rasayana property. On Hamilton Anxiety Rating Scale, patients had
anxiety, tension, depression, difficulty in concentration & memory and fear. On Hamilton Depression
Rating Scale, these patients had anxiety, depression, hypochondriasis and hopelessness. On Brief
Psychiatry Rating Scale, psychological factors affected include anxiety, depression, somatic concern
and tension etc. Medhyarasayana ghrita along with vachadi ghrita improved clinical features in
statistically highly significant (p<0.001) manner. The bio-marker serum cholinesterase showed
statistically insignificant improvement. The data reflects that disturbed mental health plays an important
role in etiopathogenesis of senile dementia. |
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