Conference Papers: Recent submissions

Now showing items 61-80 of 1239

Knowledge practices, perception and barriers of paediatric pain management among paediatric healthcare providers at Colombo North teaching hospital Ragama

Suriapperuma, T.; Dassanayeke, S.; Mettananda, S. (Sri Lanka College of Paediatricians, 2022)
Impact of covid-19 on the education and health of schooling children in Sri Lanka; A multi-provincial study

Dayasiri, K.; Thadchanamoorthy, V.; kankananarachchi, I.; Umasankar, N.; Dassanayake, S.; Gunasekara, S.; Mettananda, S. (Sri Lanka College of Paediatricians, 2022)
Efficacy of hydroxyurea in reducing the erythropoietic stress of ineffective erythropoiesis in transfusion dependent beta thalassaemia: A randomised, double-blind placebo-controlled clinical trial

Yasara, N.; Premawardhena, A.; Perera, P.; Manamperi, A.; Mettananda, S. (Sri Lanka Association for the Advancement of Science, 2021)

The unbalanced synthesis and accumulation of a-globin chains due to impaired synthesis of 0- globin results in the destruction of red blood cells (RBC) and erythroid precursors of patients with P-thalassaemia. This leads ...
In vitro study to identify effects of fetal haemoglobin inducing agents on primary human erythroid cells

Yasara, N.; Manamperi, A.; Mettananda, S. (Sri Lanka Association for the Advancement of Science, 2021)

Beta-thalassemia is an autosomal, recessively inherited monogenic disorder characterized by defective beta-globin synthesis. Deposition of excess alpha-globin in erythrocytes and their precursors due to unbalanced globin ...
Base editing repairs the HBE mutation restoring the production of normal globin chains in severe HBE/β-thalassemia patient hematopoietic stem and erythroid cells

Badat, M.; Hua, P.; Mettananda, S.; Fisher, C.; Roy, N.; Rice, S.; Roy, A.; Higgs, D.; Davies, J. (Elsevier, 2021)

HbE/β-thalassemia is the commonest form of severe β-thalassemia, and comprises approximately 50% of all cases worldwide. HbE/β-thalassemia is caused by the HbE codon 26 G>A mutation on one allele and any severe β 0-thalassemia ...
Prevalence of covishield COVID-19 vaccine (ChAdOx1 nCoV-19) adverse effects among health care workers in Sri Lanka

Manilgama, S.R.; Hettiarachchi, N.M.; Jayasinghe, K.I.; de Silva, S.; Wanigaratne, T.; Jayalath, T.; Bandusiri, R.P.; Suganthan, N.; Sudarshan, P.; Pathirage, M.; Rajaratnam, N.; Senaratne, G.; Rajapaksha, V.; Wickramasinghe, A.; Kulaweera, M.T.D. (Elsevier, 2022)

PURPOSEA Community vaccination programme is the best approach to combat COVID-19 pandemic. The first priority was given to the health care workers (HCWs) with the introduction of Indian Covishield (ChAdOx1 nCoV-19) vaccine ...
A preliminary survey for filarial parasites among dogs and cats in mahawewa, puttalam and their vector identification

Nimalrathna, S.; Mallwarachchi, C.; Chandrasena, T.G.A.N.; de Silva, N.; Kimber, M.; de Silva, N.R.; Harischandra, H. (Elsevier, 2022)

PURPOSE This study investigated the prevalence of zoonotic filarial parasites within the canine and feline population in Mahawewa, Puttalam, and their vectors based on a brugian filariasis positive human case reported to ...
Heart rate variability among gas station attendants exposed to benzene, toluene, and xylenes (BTX) in Sri Lanka

Warnakulasuriya, T.; Medagoda, K.; Kottahachchi, D.; Luke, D.; Wadasinghe, D.; de Silva, D.; Ariyawansha, J.; Rathnayaka, P.; Dissanayaka, T.; Fernando, S.; Devanarayana, N.M.; Scheepers, P.T.J. (Springer Nature., 2021)

Introduction: Benzene, toluene, and xylenes (BTX) exposure among gas station attendants in Sri Lanka is high. Cardiovascular morbidity and mortality are reported to be higher among those exposed to BTX. A hypothesis is ...
Cardiovascular autonomic functions of gas station attendants in Sri Lanka

Warnakulasuriya, T.; Medagoda, K.; Kottahachchi, D.; Luke, D.; Wadasinghe, D.; de Silva, D.; Ariyawansha, J.; Rathnayaka, P.; Dissanayaka, T.; Fernando, S.; Devanarayana, N.M. (Springer Nature., 2021)

Introduction: Sri Lanka, a middle-income country in South Asia, has seen a rapid expansion in motor vehicles and, associated with this, an increase in demand for fuel. The dispensing of fuel at fuel stations is performed ...
Comparison of urban diabetics with optimal and suboptimal control

Pinidiyapathirage, M.; Warnakulasuriya, T.; Kasturiratne, A.; Ranawaka, U.; Gunasekera, D.; Wijekoon, N.; Medagoda, K.; Perera, S.; Takeuchi, F.; Kato, N.; Wickremasinghe, A.R. (British Medical Association, London, 2011)

Introduction The prevalence of Diabetes Mellitus in Sri Lanka is increasing. We describe the characteristics of patients with optimal and suboptimal control of diabetes among known diabetics in a 35–64-year-old urban ...
Sensitization patterns of allergens among asthmatics in Sri Lanka

Weerasinghe, A.; Weerasinghe, S.; Amarasena, M.; Medagoda, K.; Katelaris, C.H. (Lippincott Williams & Wilkins, 2007)

Introduction: The sensitization pattern among asthmatics in Sri Lanka is unknown. Objectives: To determine the sensitization pattern among asthmatics in Sri Lanka. Methodology: The study was carried out in forty ...
Thyroid gland and male reproductive anomalies among fuel handlers in Gampaha district, Sri Lanka

Kottahachchi, D.C.; Warnakularuriya, T.; de Silva, D.; Madagoda, K.; Wadasinghe, D.; Dayanath, B.K.T.P.I.; Siyambalapitiya, S.; Devanarayana, N. (Endocrine Society, 2021)

Introduction:Fuel handlers at petrol stations are continuously exposed to organic solvents from fuel and vehicle emissions. Endocrine disrupting chemicals (EDC) are present in fuel, which are harmful to endocrine organs. ...
Base editing repairs the hbe mutation restoring the production of normal globin chains in severe hbe/β-Thalassemia patient hematopoietic stem and erythroid cells

Badat, M.; Hua, P.; Mettananda, S.; Fisher, C.; Roy, N.; Rice, S.; Roy, A.; Higgs, D.; Davies, J. (European Hematology Association, 2022)

Aims: HbE/β-thalassemia is the commonest form of severe β-thalassemia, and comprises approximately 50% of all cases worldwide1. HbE/β-thalassemia is caused by the HbE codon 26 G>A mutation on one allele and any β0-thalassemia ...
Adverse events following first dose of ChAdOxI nCoV-19 (Covishield) among health care workers in Sri Lanka

Manilgama, S.R.; Hettiarachchi, N.M.; Jayasinghe, I.K.; de Silva, S.; Jayalath, T.; Wanigaratne, T.; Bandusiri, R.P.; Suganthan, N.; Sudarshan, P.; Pathirage, M.; Rajaratnam, N.; Senaratne, G.; Rajapaksha, V.; Wickramasinghe, A.; Kulaweera, M.T.D. (Sri Lanka College of Internal Medicine, 2021)

Introduction: A community vaccination programme is crucial to combat COVID-19 pandemic. An independent post-vaccine surveillance is important to identify adverse events following immunization (AEFI) in the population. ...
Impact of COVID-19 on stroke admissions in a Sri Lankan tertiary care hospital:Data from the Ragama stroke registry

Deelaka, A.G.S.; Dep WDC, W.D.C.; Nanayakkara, Y.P.; Chandrasiri, H.M.J.; Mettananda, K.C.D.; Pathmeswaran, A.; Ranawaka, U.K. (Ceylon College of Physicians, 2021)

Introduction and Objectives The coronavirus disease 2019 (COVID-19) pandemic has had a tremendous impact on stroke care globally. We investigated the impact of the pandemic on stroke admissions in a Sri Lankan tertiary ...
Spontaneous intracerebral haemorrhages from a Sri Lankan tertiary care center: 5-year data

Dep, W.D.C.; Deelaka, A.G.S.; Somaratne, K.G.S.K.; Meegahapola, H.; Premadasa, H.M.S.D.; Kurukulasuriya, S.A.F.; Mettananda, K.C.D.; Ranawaka, U.K. (Ceylon College of Physicians, 2021)

Introduction and Objectives Epidemiological data on spontaneous intracerebral haemorrhage (sICH) is limited from South Asia. We sought to describe epidemiology of sICH in a Sri Lankan cohort. Methods We studied all patients ...
Changes in biochemical markers of outcomes in haemodialysis patients following a clinical pharmacy intervention.

Kalpani, A.G.S.; Mohamed, F.; Hough, J.E.; de Silva, D.N.N.; Chandrasena, W.M.H.N.M.; Jayamanne, S.F. (Ceylon College of Physicians, 2021)

Introduction and Objectives Common complications of End-Stage Renal Disease (ESRD) include cardiovascular disease, diabetes, anaemia and mineral and bone disease. Achieving an optimum level of biochemical markers of outcomes ...
Opportunities for optimization of drug therapy and characterization of drug-related problems in ckd/ckdu patients undergoing hemodialysis in Sri Lanka

Kalpani, A.G.S.; Mohamed, F.; Hough, J.E.; de Silva, D.N.N.; Jayamanne, S.F. (Ceylon College of Physicians, 2021)

Introduction and objectives Drug-related problems (DRPs) in ESRD patients undergoing haemodialysis have not been investigated in Sri Lanka. The present study was conducted to identify and characterize the potential ...
Standards of care of management of diabetes among rural cohort in Sri Lanka - a descriptive study

Chathuranga, P.A.D.U.; Meegodawidanage, N.; Rathnayaka, T.M.; Luke, W.A.N.V.; Mettananda, K.C.D. (Sri Lanka College of Internal Medicine, 2021)

Introduction: Type 2 Diabetes mellitus (T2DM) is a challenge to health care leading to increase in morbidity and mortality. Objective: We conducted a descriptive study in rural Sri Lanka to assess the standards of care and ...
Post-placental and interval intrauterine contraceptive device (IUD) insertion: does timing matter?

Dias, T.D.; Palihawadana, T.S.; Wijekoon, D.; Ganeshamoorthy, P.; Abeykoon, S.; Liyanage, G.; Padeniya, T. (Wiley-Blackwell, 2015)

INTRODUCTION Unintended pregnancies in the first year after childbirth could be high as 10–44% and expose women to consequences of induced abortion, especially in countries where termination of pregnancy is illegal. Immediate ...

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