Chemistry: Recent submissions

Now showing items 61-80 of 445

Synthesis, evaluation and structure activity relationship study of 2-phenyl-3H-quinazolinone derivatives as urease inhibitors against Helicobacter pylori

Alwis, Y. Vindula; Gunaratna, Medha J.; Udukala, Dinusha N. (Institute of Chemistry Ceylon, 2020)

Urease is a nickel containing metalloenzyme, which catalyzes the hydrolysis of urea into ammonia and carbon dioxide. It is an essential enzyme for Helicobacter pylori, which is a bacterium that has an ability to colonize ...
Evaluation of urease inhibitory activity in the testa (seed coat) and the mesocarp of Cocos nucifera variety Aurantiaca

Ranasinghe, Y. E.; Udukala, Dinusha N.; Gunaratna, Medha. J. (2020)

Helicobacter pylori is an organism in the gastric mucosa of humans, which releases the enzyme urease facilitating its colonization, leading to gastritis and gastric cancer. The existing pharmacological agents against ...
Urease inhibitory activity of the leaves and fruits of Trichosanthes cucumerina Linn.

Dharmajeewa, H. D. O. P.; Gunaratna, Medha J.; Udukala, Dinusha N. (Institute of Chemistry Ceylon, 2020)

Helicobacter pylori is a bacterium found in stomach which secretes bacterial urease, a major virulent factor to cause peptic ulcers. Hence, numerous studies have been carried out to investigate urease inhibitory activity ...
Design, synthesis and evaluation of 3-hydroxy quinazolinone derivatives as urease inhibitors against Helicobacter pylori

Ruhunage, S. A.; Udukala, Dinusha N.; Gunaratna, Medha J. (Institute of Chemistry Ceylon, 2020)

Gastritis is a common virulent disease found in the present world. The main pathogen which can cause gastritis is Helicobacter pylori and the infection from this bacterium in the upper gastrointestinal tract can lead to ...
Design, synthesis, and evaluation of 2, 3-disubstituted quinazolin-4(3H)-one derivatives as urease inhibitors against Helicobacter pylori

Madujith, E. A. D. N.; Gunaratna, Medha J.; Udukala, Dinusha N. (Institute of Chemistry Ceylon, 2020)

Helicobacter pylori is a pathogenic bacterium that causes ulcers and inflammations in the stomach lining. This bacterium produces urease enzyme which catalyzes the hydrolysis of urea in the stomach to carbon dioxide gas ...
Pyrolysis of waste polypropylene to fuel oil

Uthpalani, P. G. I.; Premachandra, J. K.; Weerasinghe, V. P. A.; De Silva, D. S. M. (Chemistry in Sri Lanka, 2022)

Plastic waste accumulation in the environment has increased rapidly. This is mainly due to their versatile properties, which allow them to be used as substitutes for wood, metals, ceramics, and glass. They have diverse ...
Changes in the Antioxidant Micronutrients and Volatile Metabolomics Profile of Selected Edible Vegetables Cooked with Coconut Milk and Heat Extracted Coconut Oil

Dewangania, H. G. Nadini; Jayawardena, Bimali; Chandrasekara, N. V.; Chandrasiri Waliwita, W. A. L. (Journal of Culinary Science & Technology, 2022)

Coconut milk, coconut oil, spices, condiments, and herbs are added to enhance flavor and aroma. The objective of the present study was to evaluate the effect of cooking methods on the total polyphenol content (TPC), ...
Probing Adaptation of Hydration and Protein Dynamics to Temperature

Doan, Luan C.; Dahanayake, Jayangika N.; Mitchell-Koch, Katie R.; Singh, Abhishek K.; Vinh, Nguyen Q. (American Chemical Society, 2022)

Protein dynamics is strongly influenced by the surrounding environment and physiological conditions. Here we employ broadband megahertz-to-terahertz spectroscopy to explore the dynamics of water and myoglobin protein ...
Ethanolic extract of rice bran: a thermally stable preservative for edible oils and cake

Seneviratne, K.P.; Anjali, N.V.P.; Senanayake, C.M. (2022)

The purpose of this study was to evaluate the thermal stability of the rice bran extract (RBE) and analyze the effect of RBE on the shelf-life of sunflower oil and the quality characteristics and shelf-life of baked cake. ...
The Groundwater Geochemistry and the Human Health Risk Assessment of Drinking Water in anArea with aHighPrevalence of Chronic Kidney Disease of Unknown Etiology (CKDu), Sri Lanka

Botheju, W. S. M; Liyanage, J. A; Kannangara, S. D. P; Corchado, J. (Journal of Chemistry, 2021, 2021)

Chronic kidney disease of unknown etiology (CKDu) has become an alarming health issue in Sri Lanka. ,e disease is more notable among farming communities and people who consume groundwater as their main source of drinking ...
Identification of Novel Bioactive Compounds, Neurosporalol 1 and 2 from anEndolichenic Fungus, Neurospora ugadawe Inhabited in the Lichen Host,Graphis tsunodae Zahlbr. from Mangrove Ecosystem in Puttalam Lagoon, Sri Lanka

Maduranga, H.; Weerasinghe, W.; Attanayake, R.; Santhirasegaram, S.; Shevkar, C.; Kate, A.S.; Weerakoon, G.; Samanthi, K.; Kalia, K.; Paranagama, P. A. (Asian Journal of Chemistry, 2021)

Endolichenic fungi (ELF) have been recognized as a promising source of bioactive secondary metabolites. Sri Lanka, a biodiversity hotspot, harbours a remarkable diversity in mangrove ecosystems. In the present study, ...
Electrodeposition of ZnS Thin Films by Complexing Agent‑Free Electrolyte Containing Sodium Thiosulfate as the Sulfur Precursor

Madhuwanthi, H.M.L.U.; Mahanama, G.D.K.; de Silva, D.S.M. (Journal of Electronic Materials, 2021)

Thin films of zinc sulphide (ZnS) were prepared by a facile, economical, and scalable electrochemical method as a buffer layer for a CdS/CdTe based solar cell. Herein, a three-electrode cell in a complexing agent-free ...
Hypoglycemic and Anti‑lipidemic Properties of Cinnamomum zeylanicum (“Sri Wijaya” Accession) Water‑soluble Nutraceutical in Streptozotocin‑induced Diabetic and Healthy Wistar Rats

Jayawardena, B.; Madushika Wariyapperuma, W.N.; Thammitiyagodage, M.; Karunakaran, R.; Sisira Kumara, W.S. (Pharmacognosy Magazine, 2021)

Background: Hyperglycemia is a serious health crisis worldwide, and more than 90% of the Sri Lankan patients effected with the condition have diabetes mellitus type 2. Natural therapeutic agents can manage the progression ...
Effect of coconut (Cocos nucifera) water extract on the development of adventitious roots in Polyscias fillicifolia stem cuttings

Jayawardena, B.M.; Agampodi, V.A.; Abeywickrama, K.P. (The Journal of Agricultural Sciences - Sri Lanka, 2021)

Purpose Vegetative propagation continues to be a popular method to propagate ornamental plant species. Coconut water (CW) can be considered as an abundant source of hormones and other plant growth regulators (PGRs). In ...
Effect of Common Culinary Methods Practiced in Sri Lanka on the Nutrient Composition of Commonly Consumed Vegetables and Other Foods

Dewangani, H.G.N.; Jayawardena, B.M.; Chandrasekara, N.V.; Wijayagunaratne, H.D.S.P. (International Journal of Food Science, 2021)

In Sri Lankan traditional cooking, coconut and spices are incorporated to enhance the taste, flavor, and aroma. However, little attention has been given to assess the effect of these ingredients on the nutritional and ...
Yoga-based Lifestyle Intervention for Prevention and Management of Type 2 Diabetes Mellitus and Associated Complications: A Clinical Research Review

Dewangani, H. N.; Jayawardena, B.; Wijayagunarathne, H. S. P. (Indian Journal of Medical Biochemistry, 2020)

Type 2 diabetes mellitus (T2DM) has become a major health challenge in the 21st century. Prevention and management of this metabolic disease could be achieved by healthy lifestyle interventions. Yoga is one such lifestyle ...
Chemical composition and antl-dlaba:tic properties In leaves of accession of cinnamon (Cinnamomum zeytanicum) Sri Wljaya and Sri Gemunu

Sonali, K.A.N.; Jayawardena, B.M. (Sri lanka association for the advancement of science, 2020)

Clnnamomum zeyJanlcum fs an evergreen tropical tree which Is proven to have hypoglycaemic properties. Proa.nthocyanidins. which are phenolic compounds beJonging to the class of flavonokls present in cinnamon are considered ...
Antioxidant, a-Amylase Inhibitory Activities and Photoprotective Properties of Peels of Nephelium Lappaceum Linn. (Malwana Special)

Binuwangi, A.K.D.M.; Perera, M.P.J.; Silva, A.A.G.; Attanayake, R.N.; Rajapakse, C.S.K. (Oriental Journal of Chemistry, 2021)

This study focused on evaluation of antioxidant, α-amylase inhibitory activities and photo protective properties of peels of Nephelium lappaceum Linn. (rambutan); Malwana special. Methanolic extract of peels was sequentially ...
Decaying Hardwood Associated Fungi Showing Signatures of Polyethylene Degradation

Perera, P.; Deraniyagala, A.S.; Mahawaththagea, M.P.S.; Herath, H.; Rajapakse, C.S.K.; Wijesinghe, P.; Attanayake, R.N. (BioResources, 2021)

The involvement of wood decay fungi and the importance of their enzymes in polyethylene degradation is well documented. Therefore, decay-resistant hardwood associated fungi should be better degraders with their versatile ...

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